|
''Polygala tenuifolia'' (Yuan Zhi) is an herb in the family Polygalaceae which is hardy to USDA Zone 6. ==Medicinal uses== Yuan Zhi is used primarily as an expectorant.〔 It is one of the 50 fundamental herbs used in traditional Chinese medicine, where it is called ''yuan zhi'' (). A randomized, double-blind, placebo-controlled, parallel-group study of the extract of dried roots of ''Polygala tenuifolia'' in healthy adults produced memory-enhancing effects.〔 A similar trial with elderly humans also found significant cognitive improvement.〔 Another study has shown that ''P. tenuifolia'' increases NGF secretion in astrocytes.〔 The root is used in Chinese medicine used for its sedative, antipsychotic, cognition improving, neuroprotective and antidepressant effect. Preclinically, Radix Polygalae extract has been shown to demonstrate a rapid-onset antidepressant-like effect. One triterpenoid saponin from the roots, Yuanzhi-1, shows significant affinity towards 5-HT, NE and DA transporters and potent antidepressant-like effects. 3,6'-disinapoyl sucrose from Polygala tenuifolia significantly inhibited MAO-A and MAO-B activity, blocked stress-induced elevations of plasma cortisol, improved hippocampal-dependent learning and memory and rescued stress-induced deficits in hippocampal neuronal plasticity and neurogenesis Radix Polygalae extract also displays anti-inflammatory activity towards microglia 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Polygala tenuifolia」の詳細全文を読む スポンサード リンク
|